Dangerous pathogens use this sophisticated machinery to infect hosts

May 17, 2019 Off By readly




Gastric cancer, Q fever, Legionnaires’ disease, whooping cough—though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells. Bacteria use this machinery, called a Type IV secretion system (T4SS), to inject toxic molecules into cells and also to spread genes for antibiotic resistance to fellow bacteria. Now, researchers at Caltech have revealed the 3-D molecular architecture of the T4SS from the human pathogen Legionella pneumophila with unprecedented details. This could in the future enable the development of precisely targeted antibiotics for the aforementioned diseases.

Source of this (above) article: https://phys.org/news/2019-05-dangerous-pathogens-sophisticated-machinery-infect.html